In another more recent study, EGFR was shown to regulate the expression of PD-L1 through the activation of Interleukin-6 (IL-6)/Janus Kinase (JAK)/signal transducer and activator of transcription 3 (STAT3) pathway in EGFR-driven NSCLC [47]. Here, CD274 is linked to non-small cell lung carcinoma.