Disease Biomarker Pathway analysis identified Myocardial Ischemia as the third most enriched pathway (FDR-adjusted p = 1.3e−2), featuring 11 SNP loci on our list out of 886 pathway objects, including annexin V, ANRIL, COL4A1, dynein, HXK4, nectin-2, PPAR-gamma, prolidase, Tcf(Lef), UGT, and VEGFR-2. The gene discussed is HNF4A; the disease is myocardial ischemia.