The tumor from patient CTC15035EML4–ALK and the CTC15035EML4–ALK xenografts generated from it contained the EML4–ALK gene fusion, and the tumor from patient CTC15063EGFR L858R, T790M and the CTC15063EGFR L858R, T790M xenografts generated from it contained the EGFR mutations, L858R and T790M. The gene discussed is EML4; the disease is neoplasm.