In the phase 2 SUMMIT basket trial, 124 patients with v-erbB2 avian eryhtorblastic leukemia viral oncogene homolog 2 (HER2) mutations and 17 patients with HER3 mutations across 21 unique tumor types were treated with neratinib, a HER2/3 inhibitor. Here, ERBB2 is linked to neoplasm.