SPTLC1 and hereditary sensory and autonomic neuropathy type 1: The failure to synthesize all or particular sphingolipids gives rise to a number of neurological conditions such as infant‐onset symptomatic epilepsy (loss of GM3 ganglioside synthesis (Simpson et al., 2004), bovine spinal muscular atrophy (loss of 3‐ketohydrosphingosine reductase (Krebs et al., 2007) and hereditary sensory and autonomic neuropathy type 1, HSAN1, recessive and dominant mutations in serine palmitoyl transferase subunit 1 ((SPTLC1), Bejaoui et al., 2001; Dawkins, Hulme, Brahmbhatt, Auer‐Grumbach, & Nicholson, 2001).