MUC1 and leukemia: Survivin inhibits caspase activation, thereby leading to the negative regulation of apoptosis and promotion of leukaemia cell survival.26 Significantly, MUC1‐C silencing in MOLM‐14/MUC1shRNA and THP1/MUC1shRNA cells resulted in the down‐regulation of survivin expression as demonstrated by decrease in both survivin mRNA (Figure 4A, B) and protein (Figure 4C) levels.