Survivin inhibits caspase activation, thereby leading to the negative regulation of apoptosis and promotion of leukaemia cell survival.26 Significantly, MUC1‐C silencing in MOLM‐14/MUC1shRNA and THP1/MUC1shRNA cells resulted in the down‐regulation of survivin expression as demonstrated by decrease in both survivin mRNA (Figure 4A, B) and protein (Figure 4C) levels. Here, BIRC5 is linked to leukemia.