MUC1‐C is an oncogenic protein aberrantly expressed in solid tumour and haematological malignancies that is known to promote malignant transformation, tissue invasion, autonomous self‐renewal and resistance to apoptosis.3, 5, 8, 12, 31, 43 MUC1 is overexpressed in majority of patients with AML.4, 7 Of note, we have demonstrated that MUC1 is uniquely expressed by AML stem cells as compared to normal haematopoietic stem cells. This evidence concerns the gene MUC1 and acute myeloid leukemia.