The GO-203 peptide, which targets the CQC motif and inhibits MUC1-C homodimerization (Fig. 2a),23,25 has been incorporated into polymeric nanoparticles (GO-203/NPs) for delivery into tumor cells.26 Treatment of MDA-MB-468 cells with GO-203/NPs was associated with the suppression of BCL2A1 mRNA and protein levels compared with empty NPs (Fig. 2d, left and right). Here, BCL2A1 is linked to neoplasm.