HNRNPU and epilepsy: The rapid turnaround time of 21 working days (14 days for urgent cases) means interventions could be started in sufficient time to theoretically modify disease course or prevent complications, although the evidence base for such therapies is yet to be established.21 In addition, we found presumed pathogenic variants in epilepsy genes that have not been well characterized including HNRNPU, and the recessive PIGT (homozygous).