The CD14 -260CT + TT genotype is found to have higher frequencies of red complex bacteria i.e. Porphyromonas gingivalis, Treponema denticola and Tannerella forsythia particularly in renal transplant patients with cyclosporine A induced gingival overgrowth which is associated with high interleukin-1β (IL-1β) levels [32]. Here, CD14 is linked to gingival overgrowth.