Converse to this is a well studied association between the cystic fibrosis and Pseudomonas aeruginosa infection in which the ∆F508 mutation in cystic fibrosis transmembrane conductance regulator (CFTR) gene lead to hypersusceptibility to chronic lung infection due to alterations in pH, ion concentrations and formation of dehydrated airway surface layer which contributes to increased proliferation of Pseudomonas aeruginosa [20, 21]. Here, CFTR is linked to cystic fibrosis.