The serum DcR3 level of the sepsis group [4.65 (0.38, 27.62) ng/mL] was significantly higher than that of the SIRS group [0.58 (0.00, 8.72) ng/mL] and control group [0.16 (0.00, 0.73 ng/mL] (both P < 0.001; Fig. 1a). The gene discussed is TNFRSF6B; the disease is systemic inflammatory response syndrome.