For example, Marques et al. found that overexpression of miR-34a using a lentiviral vector can increase the sensitivity of two DLBCL cell lines to doxorubicin (74), and circulating miR-125b and miR-130a in DLBCL is associated with R-CHOP resistance (75). Here, DDIT3 is linked to diffuse large B-cell lymphoma.