CD4 and Atherosclerotic lesion: The expression of HLA class II molecules (I-A/I-E; MHCII), an antigen presentation marker of inflammatory macrophages and contributing to LDL-derived antigen recognition by CD4+ T lymphocytes in atherosclerotic lesions (38, 39), also decreased correspondingly in p-GMSC and t-GMSC groups when compared to control groups (Figures 1E,F).