Only NFIC, a validated target of miR-210 from miRBase and a DEG from a gene expression profile GSE38135, had been shown to play important role in TGF-b1-induced osteosarcoma dedifferentiation and can be significantly reduced by miR-210 treatment in human osteosarcoma cell line MNNG/HOS [35]. The gene discussed is NFIC; the disease is osteosarcoma.