SMAD7 and neoplasm: The miR-93 targets include P21, cyclin B1 (CCNB1), ERBB2 [36], AKT serine/threonine Kinase 3 (Akt3), SRY-related HMG-box 4 (SOX4), signal transducer and activator of transcription 3 (STAT3) [37], vascular endothelial growth factor A (VEGFA) [38], and Smad7 [39], suggesting that miR-93 can be a tumor suppressor by activating different signaling pathways.