The FUMA platform (https://ctg.cncr.nl/software/fuma_gwas) highlighted that eight of the closest genes to the 44 CCT cross ethnic meta-analysis lead variants are amongst the 64 fibroblastic signature genes overexpressed in cancer cells that have undergone epithelial to mesenchymal transition24: THBS2, COL5A1, FBN1, LOXL2, DCN, LUM, COL6A2 and GLT8D2. This evidence concerns the gene FBN1 and cancer.