ZNF382 and esophageal squamous cell carcinoma: Our results indicate that inhibition of cell proliferation by ectopic expression of ZNF382 in ESCC cells might be through G2/M cell cycle arrest and apoptosis, accompanied by reduced of Cdc25C, Cdc2 and CyclinB1 checkpoint regulators and induced cleavage of apoptotic markers caspase8, caspase3 and PARP.