IL22 and colitis: Previous studies have shown that epithelial damage (e.g. induced by DSS) led to expansion and activation of RAR‐related orphan receptor gamma t (RORγt)+ ILC3s, and that deactivation of ILC3s reduced IL‐22 production and delayed the recovery from colitis.20 We thus investigated the relationship between NTPDase inhibition and intestinal ILC3s in the steady state and during colonic inflammation.