Indeed, it has been previously reported that CYP1A1 can afford some protective action against NAFLD in dioxin- [82] or B[a]P-exposed mice [22]; besides, it is known that CYP2E1 is involved in ethanol toxicity [83], even in the zebrafish model [54]. This evidence concerns the gene CYP2E1 and metabolic dysfunction-associated steatotic liver disease.