To date, only a handful of studies have explored SOX7 target genes, but none were conducted in a cancer-relevant context; SOX7 activates expression of fibroblast growth factor 3 (FGF3) [4], GATA binding protein 4 and 6 (GATA4 and GATA6) [5], laminin alpha 1 (LAMA1) [6], vascular endothelial cadherin (VE-cadherin, or CDH5) [7] and Notch1 [8]. The gene discussed is CDH5; the disease is cancer.