However, there were also studies reporting that the positive test for serum anti-PLA2R were proved to be iMN with superimposed but unrelated hepatitis virus infection or cancer (5, 45), and some scholars advocated the value of anti-PLA2R in excluding non-MN diseases, because no positive result in the test for serum anti-PLA2R has been found in patients with proteinuric condition other than MN (46). The gene discussed is PLA2R1; the disease is cancer.