Some lncRNAs, including HOTAIR [29], ANRIL [30], MALAT1 [31], and GAS5 [32], have been included in the general list of molecular biomarkers for cancer, and the number of lncRNAs has increased in the last few years, highlighting the importance of investigations into the use of lncRNAs as molecular markers in different types of cancer. This evidence concerns the gene HOTAIR and cancer.