SNAI1 and lung adenocarcinoma: Regarding the positive correlation between COPS5 and SNAIL expression in lung adenocarcinoma tissues (Figure 5), we also found the correlation between high COPS5 expression and poor survival of lung adenocarcinoma patients by analyzing the GEO datasets (GSE13213 and GSE31210) [33, 34] in Prognoscan (Supplementary Figure 4) [35]; therefore, COPS5 could be a prognostic marker for lung cancer patients.