Each of the selected miRNAs shows a large number of validated target genes (ranging from 66 to 913) which resulted significantly involved in several important KEGG (Kyoto Encyclopedia of Genes and Genomes) pathways such as MAPK signaling (for let-7c-5p, miR-10b-5p, miR-200c-3p), ErbB signaling pathway (for let-7c-5p, miR-106b-3p), and pathways in cancer/bladder cancer. The gene discussed is EGFR; the disease is urinary bladder cancer.