The gene information we recovered by annotating significant SNPs is presented in Table 4; it is noteworthy that half of the significant SNPs associated with FEW are located upstream of the histone acetyl-lysine reader, CECR2, while two candidate genes for the cat eye syndrome chromosome region, CECR1 and CECR5, were also identified. The gene discussed is HDHD5; the disease is cat-eye syndrome.