TNF and colorectal carcinoma: Among them, the presence of CRC was found to be independently positively associated with serum ZAG levels (B = 0.24, P < 0.01), which was consistent with the higher serum ZAG levels in CRC patients as displayed in Figure 1A. Serum TNF-α levels were also independently positively associated with serum ZAG levels (B = 0.01, P < 0.01), which was also in accordance with the results shown in Table 2 by partial correlation analysis.