Increased gray matter volume in frontal and hippocampal regions [7]Increased levels of neurotrophic factors (e.g., peripheral BDNF) [8]Increased blood flow [9]Increasing in academic achievement (especially children) [10]Improvements in cognitive abilities (learning and memory, attentional processes and executive processes) [11]Prevention of cognitive decline and reduced risk of developing dementia (especially in the elderly) [12]Modified network topology [13]. This evidence concerns the gene BDNF and dementia.