ANGPT2 and acute kidney injury: Yet, this indicates an earlier onset of vascular repair mechanisms which is particularly relevant owing to the fact that Angiopoietin-2 is only expressed at sites of vascular remodeling (Maisonpierre et al., 1997) and that application of synthetic Tie-2 agonistic peptide (Rubig et al., 2016) as well as VEGF (Kang et al., 2001) protects renal vascular function in experimental AKI.