In addition, apart from HAR-L dosage group, a noticeable attenuation of NO level increase was found in the other HAL, HAR, and donepezil treatment mice compared with the scopolamine-induced amnesia mice (Figure 5E, F(8,81) = 21.319, P < 0.001; F(8,81) = 12.996, P < 0.01; F(8,81) = 11.911, P < 0.01; F(8,81) = 5.227, P < 0.05; F(8,81) = 8.799, P < 0.01; F(8,81) = 17.349, P < 0.001), and the inhibitory effects of HAL on TNF-α and NO were more pronounced than those of HAR. The gene discussed is TNF; the disease is amnesia.