MPO and hypertensive disorder: They possess a significant AChE, monoamine oxidase (MAO) and myeloperoxidase (MPO) inhibitory activities, antioxidant, anti-inflammatory, antitumor, and anti-hypertension effects, and can also affect the contents of various neurotransmitters then may lead to biochemical, physiological, and behavioral changes in animals and human beings (Mahmoudian et al., 2002; Frison et al., 2008; Jiménez et al., 2008; Herraiz et al., 2010; Louis et al., 2010; Bensalem et al., 2014; Wang et al., 2015; Li et al., 2017a).