SLC1A2 and Alzheimer disease: Since synaptic connectivity is reduced in frontal cortex in AD and DLB (Jellinger, 2000; Selkoe, 2002; Hashimoto and Masliah, 2003; Gong and Lippa, 2010; Schulz-Schaeffer, 2010; Ferrer, 2012; de Wilde et al., 2016; Santpere et al., 2017), the possibility of reduced GLT1 expression secondary to decreased synaptic activity must not be overlooked in AD and DLB.