Of note, it has been recently demonstrated that the mitochondria autophagy receptor Nip3-like protein X, named NIX [also known as BCL2/adenovirus E1B 19 kDa interacting protein 3-like (BNIP3L)] can restore mitophagy and mitochondrial function in fibroblasts from PINK1-PARKIN-mutated PD Patients (Koentjoro et al., 2017). This evidence concerns the gene PRKN and Parkinson disease.