CD274 and neoplasm: Data from several studies suggested improved response of anti-PD-1antibodies in patients with PD-L1 positive tumours.22,27,29A series of trials have enroled only patients with PD-L1 positivetumours.10,16,17 Our data also suggest apossible association between anti-tumour activity and higher PD-L1 expression ontumour cells, although the number of patients is too small to make definiteconclusions.