LMX1B and nail-patella syndrome: The equivalent of LMX1A variant p.Cys97Ser has not been identified in LMX1B, but other substitutions at this position that would also impair the binding of a zinc atom, p.Cys118Phe (Vollrath et al. 1998) and p.Cys118Tyr (Clough et al. 1999), and the equivalent cysteine–serine substitution in LIM domain 1 (p.Cys59Ser), have been associated with NPS.