Interestingly, we found that TIGAR was associated with Met in NSCLC tissues (r = 0.5573, p < 0.0001) (Fig. 4a and Additional file 2: Table S2), especially in lymph node and distant organ metastases subgroup (r = 0.6576, P = 0.0003) (Additional file 3: Table S3). This evidence concerns the gene TIGAR and non-small cell lung carcinoma.