DDB2 and ovarian cancer: We transfected Tet-On pTRIPZ-inducible shDDB2 plasmids into an ovarian cancer cell line 2008, established two Tet-On-inducible DDB2 downregulation cell lines, 2008-pTRIPZ-shDDB2, and confirmed the effect of DDB2 silencing on the expansion of CSC population (Supplementary Figure S1a–h).