The etiology of craniosynostosis is complicated, however, by the fact that activating mutations in the same gene can cause a variety of different syndromes and/or types of craniosynostosis; for example, mutations in FGFR2 can cause seven of the eight FGFR-related craniosynostosis disorders, including Apert, Crouzon and Pfeiffer syndromes (Moosa and Wollnik, 2016; Robin et al., 2011). Here, FGFR2 is linked to craniosynostosis.