INS and metabolic syndrome: The underlying mechanism for the increased lactate level after non-seafood intake could be impaired insulin sensitivity in peripheral tissue, which reduces the capacity to store ingested glucose as glycogen [40,41], and consequently more of the ingested carbohydrate is converted to lactate [40], which may be used in hepatic lipogenesis resulting in dyslipidemia with elevated TAG and reduced high density lipoprotein (HDL) [41] (Figure 3).