The combined approach to weaken the effects of IL4/IL13 was more effective in asthma therapy anti-IL4/IL13 drugs and had been mainly applied in cases of mild atopic asthma and as an additional treatment, based on the inhaled corticosteroids plus a long-acting β2 agonist, in patients with uncontrolled persistent asthma [122,135]. Here, IL4 is linked to atopic asthma.