TP53 and cancer: To further confirm whether MCPIP3 regulates cancer cell migration and changes EMT-related molecule expressions in human CRC cells, we selected 10 human CRC cell lines, namely SW48, SW480, SW620, SW948, HCT8, HCT15, HT29, HCT116 p53 wild-type, HCT116 p53−/−, and DLD1.