Geniposide could reduce the mRNA and protein expressions of HIAP-1 and HIAP-2 in HSC-3 cells compared to the control cells (Figure 6), the 50 μg/m geniposide-treated cancer cells had lower HIAP-1 and HIAP-2 expressions than the 25 g/mL geniposide-treated cells, and the lowest expressions were shown by LcS-geniposide-H-treated cells. Here, BIRC3 is linked to cancer.