The vast heterogeneity of the sample collection with respect to diverse factors like platforms, origin, parts of the body, etc. positively influenced in the finding of 6 genes that had not previously related to skin cancer: SCGB2A1, CRYBA2, ANXA3, PCP4, SOSTDC1 and MYO15A. The gene discussed is SCGB2A1; the disease is skin neoplasm.