Most commonly DCM is associated with mutations in following genes: TTN, LMNA, MYH7, MYH6, SCN5A, MYBPC3, TNNT2, BAG3, ANKRD1, and TMPO. Mutations in LMNA account for ~7% of all idiopathic DCM cases (112). The gene discussed is SCN5A; the disease is familial dilated cardiomyopathy.