The observed adverse events were described previously and are known to be attributable to IL-2 and not TILs: asthenia for 6, anorexia for 3, myalgias for 2, nausea for 2, and, for 1 each thrombocytopenia, vomiting, ageusia, pruritus, cutaneous rash, flu-like syndrome, or chills. This evidence concerns the gene IL2 and asthenia.