On the contrary, fast cycling P29S, P29L, and P29Q mutations in Rac1 have been identified by high‐throughput sequencing of clinical human cancers 104, 105, 106, the G17V RhoA mutation frequent found in T cell lymphomas 107, 108 and the Y42C RhoA mutation recurrently in diffuse gastric cancer 109. This evidence concerns the gene RHOA and T-cell non-Hodgkin lymphoma.