Ectopic expression of miR-125b downregulated the EMT marker N-cadherin and the G1/S transition marker cyclin D1 and upregulated the epithelial marker E-cadherin at mRNA and protein levels, whereas co-expression of EVA1A restored expression to almost control levels, suggesting that the effect of miR-125b on suppressing EMT in HCC cells was reversed by its modulation of EVA1A expression (Figs. 5f, g). The gene discussed is CCND1; the disease is hepatocellular carcinoma.