SET and cancer: SET is ubiquitously expressed in many types of human tissues including kidney, liver, brain, spleen, lung, heart, and the gonadal system.3 Due to its role in cellular functions, its dysregulation, especially overexpression, contributes to the development of various diseases including Alzheimer's disease, polycystic ovary syndrome, and different types of cancer.4, 5, 6, 7, 8 Recently significant progress has been made in understanding the physiological and pathological functions of SET.