CARF and neoplasm: Analyses of CARF status in cancer cell lines in CCLE (Novartis/Broad 2012) TCGA dataset also revealed CARF-gene amplification and transcript enrichment in number of circulating/blood-born and invasive cancer cell lines derived either from primary or secondary metastatic tumor site (Figure S1c) suggesting that CARF may have a key role in cancer metastasis.