For instance, the G62V mutation in exon 4 [53], a heterozygous mutation (V144I) within exon 6 of the GHR [13], a dinucleotide deletion on exon 7 of the GHR gene [61], and even a GT-repeat microsatellite in the GHR 5’UTR [7] can result in dwarfism. This evidence concerns the gene GHR and Severe short stature.