IL4 and breast carcinoma: We then compared the phenotype and function of 1G (signal 1 only), 1G.4/7ICR (signals 1 + 3), 2G (signal 1 + 2), and 2G.4/7ICR (signals 1 + 2 + 3) T cells when co-cultured with MDA MB 468 breast cancer cells in the presence of IL4 (400 U/mL) (Fig. 3).