There were many statistically significant correlations between RBP4, TTR, and HOMA-IR, with metabolic syndrome parameters including RBP4 correlated with TG (r = 0.344) and HDL-c (r = 0.259); TTR correlated with FBG (r = 0.182), TG (r = 0.260), and HDL-c (r = 0.168) was also significant; HOMA-IR correlated with FBG (r = 0.216), TG (r = 0.160), and HDL-c (r = 0.186). The gene discussed is RBP4; the disease is metabolic syndrome.