MAVS and B-cell non-Hodgkin lymphoma: To examine the effect of MAVS on HHV-8 infection, the expression of MAVS was genetically ablated by CRISPR/Cas9-mediated mutagenesis in BCBL-1, an HHV-8-infected PEL cell line, and control HHV-8-negative BJAB B-cell lymphoma cells.